HYDROGEN SULFIDE ATTENUATES PM2.5-INDUCED COPD BY INHIBITING CELLULAR SENESCENCE VIA THE KLOTHO/PARKIN-MEDIATED MITOPHAGY SIGNALING PATHWAY

Hydrogen sulfide attenuates PM2.5-induced COPD by inhibiting cellular senescence via the Klotho/Parkin-mediated mitophagy signaling pathway

Fine particulate matter (PM2.5), an atmospheric pollutant, plays a crucial role in mediating the occurrence of chronic obstructive pulmonary disease (COPD).Hydrogen sulfide (H2S) has shown therapeutic potential in countering COPD, but Scoop Plus the underlying mechanisms remain elusive.This study aimed to elucidate the potential mechanisms of H2S i

read more

Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases

Summary: Mislocalization, cleavage, and aggregation of the human protein TDP-43 is found in Precut Fused Applique Shapes many neurodegenerative diseases.As is the case with many other proteins that are completely or partially structurally disordered, production of full-length recombinant TDP-43 in the quantities necessary for structural characteriz

read more